Animals
Only in Florida: Gator hijacks watermelon - CBS News
"Gator caught stealing watermelon out of watermelon field in Hendry County,"
Cancer
Melatonin | University of Maryland Medical Center
When it is dark, your body produces more melatonin. When it is light, the production of melatonin drops. Being exposed to bright lights in the evening, or too little light during the day, can disrupt the body's normal melatonin cycles. Both abnormal light/dark cycles and low melatonin levels have been related to cancer.
Is prostate cancer incidence worldwide linked to artificial light at night exposures? Review of earlier findings and analysis of current trends. - PubMed - NCBI
Widespread use of artificial light at night (ALAN) might contribute to the global burden of hormone-dependent cancers. Association between ALAN and prostate cancer (PC) incidence was significant (t > 2.7; p < .01) when 110 countries with well-maintained cancer registries were analyzed. Along with other variables, ALAN explains up to 79% of PC ASR variability.
Can Avoiding Light at Night Reduce the Risk of Breast Cancer? - PubMed - NCBI
Excessive exposure to artificial light at night (ALAN) suppresses nocturnal melatonin (MLT) production in the pineal gland and is, therefore, associated with an increased risk of breast cancer
Melatonin inhibits tumorigenicity of glioblastoma stem-like cells via the AKT-EZH2-STAT3 signaling axis. - PubMed - NCBI
melatonin attenuated multiple key signals involved in GSC self-renewal and survival, and further supported melatonin as a promising GBM therapeutic.
Melatonin as a potential anticarcinogen for non-small-cell lung cancer. - PubMed - NCBI
a comprehensive reference for the anticancer mechanisms of melatonin against NSCLC, and may be helpful for the design of future experimental research and for advancing melatonin as a therapeutic agent for NSCLC.
Melatonin prevents cisplatin-induced primordial follicle loss via suppression of PTEN/AKT/FOXO3a pathway activation in the mouse ovary. - PubMed - NCBI
Melatonin is a potential therapeutic agent for ovarian protection and fertility preservation during chemotherapy in female cancer patients.
Synergic Effects of Doxorubicin and Melatonin on Apoptosis and Mitochondrial Oxidative Stress in MCF-7 Breast Cancer Cells: Involvement of TRPV1 Ch... - PubMed - NCBI
As the apoptosis and caspase activity of cancer cells increase because of their elevated metabolism, MEL may be useful in supporting their apoptotic capacity
Sustained release of melatonin: A novel approach in elevating efficacy of tamoxifen in breast cancer treatment. - PubMed - NCBI
Taken together, our results suggest NLC technology as a promising delivery system, which elevates the efficacy of chemotherapeutics in breast cancer cells.
The genotoxic effects of anti-cancer drug gossypol on human lymphocytes and its mitigation by melatonin. - PubMed - NCBI
Gossypol, an anti-cancer drug, induces genotoxicity on lymphocyte cells and co-supplementation of melatonin antioxidant ameliorates these toxic effects of gossypol.